Steroids are an item in Duke Nukem Forever.



Bottle of steroids in The Lady Killer: Part 2.

When used, Steroids place Duke's Ego at 75% of maximum, and increase his melee strength to 128, at the cost of restricting Duke to melee combat while under their effects. This makes the user very effective in melee combat, as they can quickly run up to an enemy and easily beat them to death (gibs) with their melee attack. Like in Duke Nukem 3D, they can be picked up and used whenever the player wants to.

They are labeled "Nukem RX". Additionally, there are a few posters throughout the game advertising them, accompanied by a picture of Duke from Land of the Babes and the slogan "Pump or die, baby!"

Steroids are usable in both single and multiplayer modes. There are multiple Achievements/Trophies involved with using Steroids, including "Substance Abuser", where the player has to take Steroids and Beer at the same time.

The steroids in DNF act more like the Berserker from Doom, with more melee damage and only melee.


  • In DNF, the steroids only increase melee strength. In DN3D, they increase speed, melee strength and make the player immune to shrink rays.
Duke Nukem Forever
Chapters Duke Lives | Damn! It's Late... | The Duke Cave | Mothership Battle | The Lady Killer | Vegas in Ruin | The Duke Dome | The Hive | Queen Bitch | Duke Nukem's Titty City | Crash Course | The Duke Burger | The Mighty Foot | Ghost Town | Highway Battle | Dam Top | The Shrunk Machine | The Forkstop | Generator Room | Underground | The Clarifier | Blowin' the Dam | Final Battle | Press Conference
Items Beer | Duke Vision | Holoduke | Jetpack | Steroids | Double Damage | Invincibility
Weapons Melee | M1911 Pistol | Shotgun | Ripper | RPG | Pipe Bomb | Trip Mine | Railgun
Shrink Ray | Freeze Ray | AT Laser | AT Captain Laser | Enforcer Gun | Devastator | Expander | Impregnader | Garter Pistol | Sticky Bombs | Tittyana | DFG | N00b T00b
Scrapped: Assault Rifle | Chainsaw | Shield
Enemies Assault Commander | Enforcer | Assault Trooper
Assault Trooper Captain | Octabrain | Pigcop | Pregnator | Octababy | Rat
Bosses: Cycloid Emperor | Mothership | Battlelord | Alien Queen | Octaking | Energy Leech
Scrapped: Robot | Army Ant | Mutated Human | Human Robot
Other Difficulty | Hazards | EGO | Multiplayer | Cheat codes | Easter eggs
Quotes | Music | Creators | Duke Nukem
Game bugs
Hail to the Icons Parody Pack
The Doctor Who Cloned Me
Community content is available under CC-BY-SA unless otherwise noted.