Redneck Rampage is a game that relates closely to Duke Nukem 3D, in terms of the game's engine. This game however focuses more on redneck and hillbilly stereotypes than on strip club humor, though both games are themed around an alien invasion.

Unlike Duke Nukem 3D, Redneck Rampage relies on an audio CD for the game's soundtrack. Incidentally, the CD-ROM for the game was playable as also a standard audio CD thus making it a "soundtrack album" for the game. Similarly, other CD-ROM games around that time had the dual-function of being a soundtrack album.