Flamethrower may refer to:
- Two easily confused weapons from Duke Nukem 3D:
- Flamethrower (DN3D), a scrapped weapon that appeared in prototypes
- Incinerator, a weapon introduced in Duke Nukem 3D: 20th Anniversary World Tour
- Flamethrower (DN2), a weapon in Duke Nukem II
- Flamethrower (DNLOTB), a weapon in Duke Nukem: Land of the Babes
- Flamethrower (DNTTK), a weapon in Duke Nukem: Time to Kill