Duke Nukem Mobile may refer to:
- Duke Nukem Mobile (Side-Scroller), a 2D side-scrolling game for mobile phones
- Duke Nukem Mobile (Tapwave Zodiac), a 3D first-person shooter for the Tapwave Zodiac
- Duke Nukem Mobile 3D, a 3D first-person shooter for mobile phones
- Duke Nukem Mobile Arena, another 3D first-person shooter for mobile phones
- Duke Nukem Mobile: Bikini Project, a sequel to the side-scrolling Duke Nukem Mobile