Duke Nukem Wiki

Big Mama appears to be a scrapped Mutated Human for Duke Nukem Forever.


Big Mama has the appearance of a bloated human female with her right arm heavily mutated. She also appears to have an incision in her body, which in most concepts is in her abdominal region, that may allow for an alien to expose itself.


Big Mama was never featured as an enemy in Duke Nukem Forever or any of its trailers, however, her concept art can be viewed after the player unlocks the extras after beating the game.


Most concepts of Big Mama portray her wearing thigh high nylons, having a tattoo of a heart on one of her breasts, and her hair tied up in a bun or ponytail, strongly suggesting her to having once been a human female.